The Sinai Robotic Surgery Trial in HPV-related oropharyngeal squamous cell carcinoma (SIRS 2.0 trial) – study protocol for a phase II non-randomized non-inferiority trial

The Sinai Robotic Surgery Trial in HPV-related oropharyngeal squamous cell carcinoma (SIRS 2.0 trial) – study protocol for a phase II non-randomized non-inferiority trial

BackgroundHuman papillomavirus associated oropharyngeal squamous cell carcinoma (HPVOPSCC) usually affects a younger patient population. As such, the risk for long term toxicity associated with therapy is an important consideration. Multiple trials focused on de-escalation of therapy to preserve sur...

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Bibliographic Details
Main Authors: Raymond L. Chai, Rocco M. Ferrandino, Christine Barron, Kianoush Donboli, Scott A. Roof, Mohemmed N. Khan, Marita S. Teng, Marshall R. Posner, Richard L. Bakst, Eric M. Genden
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Oncology
Subjects:
de-escalation
human papillomavirus
oropharynx cancer
transoral robotic surgery
circulating tumor DNA (ctDNA)
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.965578/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.965578/full

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