Tissue Inhibitor of Metalloproteases 3 (TIMP-3): In Vivo Analysis Underpins Its Role as a Master Regulator of Ectodomain Shedding
The proteolytical cleavage of transmembrane proteins with subsequent release of their extracellular domain, so-called ectodomain shedding, is a post-translational modification that plays an essential role in several biological processes, such as cell communication, adhesion and migration. Metallopro...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-02-01
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Series: | Membranes |
Subjects: | |
Online Access: | https://www.mdpi.com/2077-0375/12/2/211 |