Investigating Shared Genetic Bases between Psychiatric Disorders, Cardiometabolic and Sleep Traits Using K-Means Clustering and Local Genetic Correlation Analysis

Investigating Shared Genetic Bases between Psychiatric Disorders, Cardiometabolic and Sleep Traits Using K-Means Clustering and Local Genetic Correlation Analysis

Psychiatric disorders are among the top leading causes of the global health-related burden. Comorbidity with cardiometabolic and sleep disorders contribute substantially to this burden. While both genetic and environmental factors have been suggested to underlie these comorbidities, the specific mol...

Full description

Bibliographic Details
Main Authors: Gianpaolo Zammarchi, Claudio Conversano, Claudia Pisanu
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Algorithms
Subjects:
GWAS
k-means clustering
mendelian randomization
genetic correlation
pleiotropy
major depressive disorder
Online Access:https://www.mdpi.com/1999-4893/15/11/409

Internet

https://www.mdpi.com/1999-4893/15/11/409

Similar Items