TCEAL7 Inhibition of c-Myc Activity in Alternative Lengthening of Telomeres Regulates hTERT Expression

TCEAL7 Inhibition of c-Myc Activity in Alternative Lengthening of Telomeres Regulates hTERT Expression

Replicative senescence forms a major barrier to tumor progression. Cancer cells bypass this by using one of the two known telomere maintenance mechanisms: telomerase or the recombination-based alternative lengthening of telomeres (ALT) mechanism. The molecular details of ALT are currently poorly und...

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Bibliographic Details
Main Authors: Kyle Lafferty-Whyte, Alan Bilsland, Stacey F. Hoare, Sharon Burns, Nadia Zaffaroni, Claire J. Cairney, William Nicol Keith
Format: Article
Language:English
Published: Elsevier 2010-05-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558610800582

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http://www.sciencedirect.com/science/article/pii/S1476558610800582

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