Inhibiting the compensatory elevation of xCT collaborates with disulfiram/copper-induced GSH consumption for cascade ferroptosis and cuproptosis
Hepatocellular carcinoma (HCC) is one of the most prevalent malignant tumors and the fourth leading cause of cancer-related death globally, which is characterized by complicated pathophysiology, high recurrence rate, and poor prognosis. Our previous study has demonstrated that disulfiram (DSF)/Cu co...
Main Authors: | Ping Zhang, Chaoting Zhou, Xueying Ren, Qiangan Jing, Yan Gao, Chen Yang, Yuhuan Shen, Yi Zhou, Wanye Hu, Feifan Jin, Haifeng Xu, Lingyan Yu, Yingchao Liu, Xiangmin Tong, Yanchun Li, Ying Wang, Jing Du |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2024-02-01
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Series: | Redox Biology |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2213231723004081 |
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