Liraglutide Has Anti-Inflammatory and Anti-Amyloid Properties in Streptozotocin-Induced and 5xFAD Mouse Models of Alzheimer’s Disease

Liraglutide Has Anti-Inflammatory and Anti-Amyloid Properties in Streptozotocin-Induced and 5xFAD Mouse Models of Alzheimer’s Disease

Recent clinical and epidemiological studies support the contention that diabetes mellitus (DM) is a strong risk factor for the development of Alzheimer’s disease (AD). The use of insulin cell toxin, streptozotocin (STZ), when injected into the lateral ventricles, develops an insulin resistant brain...

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Bibliographic Details
Main Authors: Leela Paladugu, Abeer Gharaibeh, Nivya Kolli, Cameron Learman, Tia C. Hall, Lixin Li, Julien Rossignol, Panchanan Maiti, Gary L. Dunbar
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Molecular Sciences
Subjects:
Alzheimer’s disease
liraglutide
streptozotocin
neuroinflammation
amyloid beta protein
sporadic Alzheimer’s disease
Online Access:https://www.mdpi.com/1422-0067/22/2/860

Internet

https://www.mdpi.com/1422-0067/22/2/860

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