Highly Accurate Prediction of Protein-Protein Interactions via Incorporating Evolutionary Information and Physicochemical Characteristics

Highly Accurate Prediction of Protein-Protein Interactions via Incorporating Evolutionary Information and Physicochemical Characteristics

Protein-protein interactions (PPIs) occur at almost all levels of cell functions and play crucial roles in various cellular processes. Thus, identification of PPIs is critical for deciphering the molecular mechanisms and further providing insight into biological processes. Although a variety of high...

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Bibliographic Details
Main Authors: Zheng-Wei Li, Zhu-Hong You, Xing Chen, Jie Gui, Ru Nie
Format: Article
Language:English
Published: MDPI AG 2016-08-01
Series:International Journal of Molecular Sciences
Subjects:
evolutionary information
physicochemical characteristics
protein sequence
protein interactions
discriminative vector machine
Online Access:http://www.mdpi.com/1422-0067/17/9/1396

Internet

http://www.mdpi.com/1422-0067/17/9/1396

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