Inhibitory Effects of Acetylmelodorinol, Chrysin and Polycarpol from Mitrella kentii on Prostaglandin E2 and Thromboxane B2 Production and Platelet Activating Factor Receptor Binding

Inhibitory Effects of Acetylmelodorinol, Chrysin and Polycarpol from Mitrella kentii on Prostaglandin E2 and Thromboxane B2 Production and Platelet Activating Factor Receptor Binding

Acetylmelodorinol, chrysin and polycarpol, together with benzoic acid, benzoquinone and stigmasterol were isolated from the leaves of Mitrella kentii (Bl.) Miq. The compounds were evaluated for their ability to inhibit prostaglandin E2 (PGE2) and thromboxane B2 (TXB2) production in human whole blood...

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Bibliographic Details
Main Authors: Ibrahim Jantan, Malina Jasamai, Juriyati Jalil, Sakina Saadawi
Format: Article
Language:English
Published: MDPI AG 2012-04-01
Series:Molecules
Subjects:
Mitrella kentii
chrysin
acetylmelodorinol
polycarpol
prostaglandin E2 (PGE2)
thromboxane B2 (TXB2)
platelet activating factor (PAF) antagonist
Online Access:http://www.mdpi.com/1420-3049/17/5/4824/

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http://www.mdpi.com/1420-3049/17/5/4824/

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