Tmprss6-ASO as a tool for the treatment of Polycythemia Vera mice.

Tmprss6-ASO as a tool for the treatment of Polycythemia Vera mice.

Polycythemia Vera (PV) is a chronic myeloproliferative neoplasm resulting from an acquired driver mutation in the JAK2 gene of hematopoietic stem and progenitor cells resulting in the overproduction of mature erythrocytes and abnormally high hematocrit, in turn leading to thromboembolic complication...

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Bibliographic Details
Main Authors: Carla Casu, Alison Liu, Gianluca De Rosa, Audrey Low, Aae Suzuki, Sayantani Sinha, Yelena Z Ginzburg, Charles Abrams, Mariam Aghajan, Shuling Guo, Stefano Rivella
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0251995

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https://doi.org/10.1371/journal.pone.0251995

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