Mouse models of graft-versus-host disease: advances and limitations

The limiting factor for successful hematopoietic stem cell transplantation (HSCT) is graft-versus-host disease (GvHD), a post-transplant disorder that results from immune-mediated attack of recipient tissue by donor T cells contained in the transplant. Mouse models of GvHD have provided important in...

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Bibliographic Details
Main Authors: Mark A. Schroeder, John F. DiPersio
Format: Article
Language:English
Published: The Company of Biologists 2011-05-01
Series:Disease Models & Mechanisms
Online Access:http://dmm.biologists.org/content/4/3/318