Mouse models of graft-versus-host disease: advances and limitations
The limiting factor for successful hematopoietic stem cell transplantation (HSCT) is graft-versus-host disease (GvHD), a post-transplant disorder that results from immune-mediated attack of recipient tissue by donor T cells contained in the transplant. Mouse models of GvHD have provided important in...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2011-05-01
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Series: | Disease Models & Mechanisms |
Online Access: | http://dmm.biologists.org/content/4/3/318 |