AAV Engineering for Improving Tropism to the Central Nervous System

Adeno-associated virus (AAV) is a non-pathogenic virus that mainly infects primates with the help of adenoviruses. AAV is being widely used as a delivery vector for in vivo gene therapy, as evidenced by five currently approved drugs and more than 255 clinical trials across the world. Due to its rela...

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Bibliographic Details
Main Authors: Muhammad S. Ghauri, Li Ou
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Biology
Subjects:
Online Access:https://www.mdpi.com/2079-7737/12/2/186