HLA Class I-T cell epitopes from trans-sialidase proteins reveal functionally distinct subsets of CD8+ T cells in chronic Chagas disease.

HLA Class I-T cell epitopes from trans-sialidase proteins reveal functionally distinct subsets of CD8+ T cells in chronic Chagas disease.

BACKGROUND:Previously, we identified a set of HLA-A020.1-restricted trans-sialidase peptides as targets of CD8+ T cell responses in HLA-A0201+ individuals chronically infected by T. cruzi. METHODS AND FINDINGS:Herein, we report the identification of peptides encoded by the same trans-sialidase gene...

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Bibliographic Details
Main Authors: María G Alvarez, Miriam Postan, D Brent Weatherly, María C Albareda, John Sidney, Alessandro Sette, Carina Olivera, Alejandro H Armenti, Rick L Tarleton, Susana A Laucella
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18846233/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18846233/?tool=EBI

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