Macrophage elastase derived from adventitial macrophages modulates aortic remodeling

Macrophage elastase derived from adventitial macrophages modulates aortic remodeling

Abdominal aortic aneurysm (AAA) is pathologically characterized by intimal atherosclerosis, disruption and attenuation of the elastic media, and adventitial inflammatory infiltrates. Although all these pathological events are possibly involved in the pathogenesis of AAA, the functional roles contrib...

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Bibliographic Details
Main Authors: Yajie Chen, Xiawen Yang, Shuji Kitajima, Longquan Quan, Yao Wang, Maobi Zhu, Enqi Liu, Liangxue Lai, Haizhao Yan, Jianglin Fan
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
MMP-12
macrophage
elastin
abdominal aortic aneurysm
transgenic rabbits
atherosclerosis
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.1097137/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2022.1097137/full

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