GDF15 is an exercise-induced hepatokine regulated by glucagon and insulin in humans

GDF15 is an exercise-induced hepatokine regulated by glucagon and insulin in humans

ObjectiveGrowth differentiation factor (GDF)-15 is implicated in regulation of metabolism and circulating GDF15 increases in response to exercise. The source and regulation of the exercise-induced increase in GDF15 is, however not known.MethodPlasma GDF15 was measured by ELISA under the following co...

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Bibliographic Details
Main Authors: Peter Plomgaard, Jakob S. Hansen, Logan K. Townsend, Anders Gudiksen, Niels H. Secher, Jens O. Clemmesen, Rene K. Støving, Jens P. Goetze, David C. Wright, Henriette Pilegaard
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Endocrinology
Subjects:
fasting
liver
splanchnic bed
appetite
insulin resistance
anorexia nervosa
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.1037948/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2022.1037948/full

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