Identification of Host PDZ-Based Interactions with the SARS-CoV-2 E Protein in Human Monocytes

Identification of Host PDZ-Based Interactions with the SARS-CoV-2 E Protein in Human Monocytes

Proteins containing PDZ (post-synaptic density, PSD-95/disc large, Dlg/zonula occludens, ZO-1) domains assemble signaling complexes that orchestrate cell responses. Viral pathogens target host PDZ proteins by coding proteins containing a PDZ-binding motif (PBM). The presence of a PBM in the SARS-CoV...

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Bibliographic Details
Main Authors: Antonia Ávila-Flores, Juan José Sánchez-Cabezón, Ane Ochoa-Echeverría, Ana I. Checa, Jorge Rosas-García, Mariana Téllez-Araiza, Sara Casado, Rosa Liébana, Teresa Santos-Mendoza, Isabel Mérida
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:International Journal of Molecular Sciences
Subjects:
SARS-CoV-2
envelope (E) protein
PDZ
monocyte
innate immune response
syntenin
Online Access:https://www.mdpi.com/1422-0067/24/16/12793

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https://www.mdpi.com/1422-0067/24/16/12793

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