On the action of cyclosporine A, rapamycin and tacrolimus on M. avium including subspecies paratuberculosis.

BACKGROUND: Mycobacterium avium subspecies paratuberculosis (MAP) may be zoonotic. Recently the "immuno-modulators" methotrexate, azathioprine and 6-MP and the "anti-inflammatory" 5-ASA have been shown to inhibit MAP growth in vitro. We concluded that their most plausible mechani...

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Bibliographic Details
Main Authors: Robert J Greenstein, Liya Su, Ramon A Juste, Sheldon T Brown
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2427180?pdf=render