The clinical significance of CTC enrichment by GPC3-IML and its genetic analysis in hepatocellular carcinoma

The clinical significance of CTC enrichment by GPC3-IML and its genetic analysis in hepatocellular carcinoma

Abstract Background This research was to develop a special method for enriching Circulating tumor cells (CTCs) of Hepatocellular carcinoma (HCC) by Glypican-3 immunoliposomes (GPC3-IML), and to analyze the correlation between the CTCs count and tumor malignancy, as well as to investigate the mutatio...

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Bibliographic Details
Main Authors: Bin Yi, Tian Wu, Nan Zhu, Yao Huang, Xiaoyu Yang, Lei Yuan, Yingjun Wu, Xiaofei Liang, Xiaoqing Jiang
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Journal of Nanobiotechnology
Subjects:
Hepatocellular carcinoma (HCC)
Circulating tumor cells (CTCs)
Glypican-3 (GPC-3)
GPC3 immunoliposomes (GPC3-IML)
Next generation sequencing (NGS)
Online Access:https://doi.org/10.1186/s12951-021-00818-3

Internet

https://doi.org/10.1186/s12951-021-00818-3

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