Resveratrol protection against IL-1β-induced chondrocyte damage via the SIRT1/FOXO1 signaling pathway

Resveratrol protection against IL-1β-induced chondrocyte damage via the SIRT1/FOXO1 signaling pathway

Abstract Purpose Osteoarthritis (OA) is a common joint disease characterized by cartilage degeneration, synovial inflammation, osteophytes, and subchondral osteosclerosis. This study investigated the effects of resveratrol (RES) on extracellular matrix (ECM), autophagy, and apoptosis in OA pathogene...

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Bibliographic Details
Main Authors: ChuanCai Liang, Hengte Xing, ChenYu Wang, XiongFeng Xu, Yarong Hao, Bo Qiu
Format: Article
Language:English
Published: BMC 2022-09-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Chondrocytes
Extracellular matrix
Apoptosis
Autophagy
Resveratrol
Osteoarthritis
Online Access:https://doi.org/10.1186/s13018-022-03306-y

Internet

https://doi.org/10.1186/s13018-022-03306-y

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