The Implication of the Polymorphisms of COX-1, UGT1A6, and CYP2C9 among Cardiovascular Disease (CVD) Patients Treated with Aspirin

The Implication of the Polymorphisms of COX-1, UGT1A6, and CYP2C9 among Cardiovascular Disease (CVD) Patients Treated with Aspirin

PURPOSE:  Enzymes potentially responsible for the pharmacokinetic variations of aspirin include cyclooxygenase-1 (COX-1), UDP-glucuronosyltransferase (UGT1A6) and P450 (CYP) (CYP2C9). We therefore aimed to determine the types and frequencies of variants of COX-1 (A-842G), UGT1A6 (UGT1A6*2; A541G and...

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Bibliographic Details
Main Authors: Nur Jalinna Abdul Jalil, Zakaria Bannur, A. Derahman, O. Maskon, Noor Darinah, Hamat Hamidi, Osama Ali Gunasekaran, Mohd Rafizi, Nur Izatul Azreen, Teh Lay Kek, Mohd. Zaki Salleh
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-09-01
Series:Journal of Pharmacy & Pharmaceutical Sciences
Online Access:https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/24226

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https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/24226

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