Genomic analysis of penicillin-binding proteins and recombination events in an emerging amoxicillin- and meropenem-resistant PMEN3 (Spain9V-3, ST156) variant in Taiwan and comparison with global descendants of this lineage

Genomic analysis of penicillin-binding proteins and recombination events in an emerging amoxicillin- and meropenem-resistant PMEN3 (Spain9V-3, ST156) variant in Taiwan and comparison with global descendants of this lineage

ABSTRACT From 2008 to 2020, the Taiwan National Notifiable Disease Surveillance System database demonstrated that the incidence of non-vaccine serotype 23A invasive pneumococcal disease (IPD) approximately doubled. In this study, 276 non-repetitive pneumococcal clinical isolates were collected from...

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Bibliographic Details
Main Authors: Yi-Yin Chen, Hsin Chi, Wei-Chao Liao, Shiao-Wen Li, Yu-Ching Yang, Ho-Chen Lin, Hsiao-Pei Chang, Yi-Jiun Pan, Ruei-Lin Chiang, Yu-Chia Hsieh
Format: Article
Language:English
Published: American Society for Microbiology 2023-12-01
Series:Microbiology Spectrum
Subjects:
clonal shift
antibiotic resistant
non-vaccine serotype
β-lactam resistant
PMEN3 variant
Streptococcus pneumoniae
Online Access:https://journals.asm.org/doi/10.1128/spectrum.01840-23

Internet

https://journals.asm.org/doi/10.1128/spectrum.01840-23

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