Experimental Study on the Bone Morphogenetic Protein 1-Modified Bone Marrow Mesenchymal Stem Cell Sheets to Promote Mandibular Distraction Osteogenesis

Experimental Study on the Bone Morphogenetic Protein 1-Modified Bone Marrow Mesenchymal Stem Cell Sheets to Promote Mandibular Distraction Osteogenesis

ObjectiveThe present study aims to increase the concentration of genetically modified bone marrow mesenchymal stem cells (BMSCs) in the distraction osteogenesis (DO) interstitial space and induce the conversion of BMSCs to osteoblasts to improve the osteogenic efficiency in DO and shorten the treatm...

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Bibliographic Details
Main Authors: Zhong-Ping Su, Lei Tian, Hong-Tao Shang, Yong Yang, Jin-Biao Lu, Yong-Jie Kang, Li-Sheng He, Jin-Long Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Surgery
Subjects:
distraction osteogenesis
bone marrow stromal stem cells
bone morphogenetic protein-1
cell sheet
osteogenic efficiency
Online Access:https://www.frontiersin.org/articles/10.3389/fsurg.2021.786351/full

Internet

https://www.frontiersin.org/articles/10.3389/fsurg.2021.786351/full

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