Design, characterization of Resveratrol-Thermosensitive Hydrogel System (Res-THS) and evaluation of its anti-depressant effect via intranasal administration

Thermosensitive Hydrogel System (THS) is a suitable candidate for targeted drug delivery, because of its intelligent response and controlled release. In this work, combination of guanidine-chitosan (GCS), β-glycerol phosphate disodium salt (β-GP) and hydroxypropyl-β-cyclodextrin (HP-β-CD) can succes...

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Bibliographic Details
Main Authors: Jin-Feng Zhou, LiLi Duan, Yu-Xin Wang, Chen-Lin Wang, Meng-Li Tian, Xue-Jie Qi, Feng Qiu
Format: Article
Language:English
Published: Elsevier 2022-04-01
Series:Materials & Design
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0264127522002180