G-protein-coupled receptor signaling and polarized actin dynamics drive cell-in-cell invasion
Homotypic or entotic cell-in-cell invasion is an integrin-independent process observed in carcinoma cells exposed during conditions of low adhesion such as in exudates of malignant disease. Although active cell-in-cell invasion depends on RhoA and actin, the precise mechanism as well as the underlyi...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2014-06-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/02786 |