Carvacrol instigates intrinsic and extrinsic apoptosis with abrogation of cell cycle progression in cervical cancer cells: Inhibition of Hedgehog/GLI signaling cascade

Carvacrol instigates intrinsic and extrinsic apoptosis with abrogation of cell cycle progression in cervical cancer cells: Inhibition of Hedgehog/GLI signaling cascade

Recent times have seen a strong surge in therapeutically targeting the hedgehog (HH)/GLI signaling pathway in cervical cancer. HH signaling pathway is reported to be a crucial modulator of carcinogenesis in cervical cancer and is also associated with recurrence and development of chemoresistance. Mo...

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Bibliographic Details
Main Authors: Afza Ahmad, Rohit Kumar Tiwari, Mohd Saeed, Hadba Al-Amrah, Ihn Han, Eun-Ha Choi, Dharmendra K. Yadav, Irfan Ahmad Ansari
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Chemistry
Subjects:
beta-glucan
antioxidant activity
apoptosis
anticancer
cervical cancer
ROS generation
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2022.1064191/full

Internet

https://www.frontiersin.org/articles/10.3389/fchem.2022.1064191/full

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