KMT2B promotes the growth of renal cell carcinoma via upregulation of SNHG12 expression and promotion of CEP55 transcription

KMT2B promotes the growth of renal cell carcinoma via upregulation of SNHG12 expression and promotion of CEP55 transcription

Abstract Background This study aims to clarify the mechanistic action of long non-coding RNA (lncRNA) SNHG12 in the development of renal cell carcinoma (RCC), which may be associated with promoter methylation modification by KMT2B and the regulation of the E2F1/CEP55 axis. Methods TCGA and GEO datab...

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Bibliographic Details
Main Authors: Jia-fu Feng, Jun Wang, Gang Xie, Yao-dong Wang, Xiao-han Li, Wen-yu Yang, Yu-wei Yang, Bin Zhang
Format: Article
Language:English
Published: BMC 2022-05-01
Series:Cancer Cell International
Subjects:
Renal cell carcinoma
KMT2B
Long non-coding RNA
SNHG12
E2F1
CEP55
Online Access:https://doi.org/10.1186/s12935-022-02607-w

Internet

https://doi.org/10.1186/s12935-022-02607-w

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