Toward an Early Diagnosis for Alzheimer’s Disease Based on the Perinuclear Localization of the ATM Protein

Toward an Early Diagnosis for Alzheimer’s Disease Based on the Perinuclear Localization of the ATM Protein

Alzheimer’s disease (AD) is the most common neurodegenerative dementia, for which the molecular origins, genetic predisposition and therapeutic approach are still debated. In the 1980s, cells from AD patients were reported to be sensitive to ionizing radiation. In order to examine the molecular basi...

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Bibliographic Details
Main Authors: Elise Berthel, Laurent Pujo-Menjouet, Eymeric Le Reun, Laurène Sonzogni, Joëlle Al-Choboq, Abdennasser Chekroun, Adeline Granzotto, Clément Devic, Mélanie L. Ferlazzo, Sandrine Pereira, Michel Bourguignon, Nicolas Foray
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Cells
Subjects:
Alzheimer’s disease
ATM
APOE
aging
fibroblasts
immunofluorescence
Online Access:https://www.mdpi.com/2073-4409/12/13/1747

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https://www.mdpi.com/2073-4409/12/13/1747

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