TET2 mutations in acute myeloid leukemia: a comprehensive study in patients of Sindh, Pakistan

TET2 mutations in acute myeloid leukemia: a comprehensive study in patients of Sindh, Pakistan

Background The tet oncogene family member 2 (TET2) gene has been reported to be involved in DNA methylation and epigenetic regulation in acute myeloid leukemia (AML). Various studies have proven functional role of TET2 mutations in AML. We herein studied the frequency and genotype-phenotype correlat...

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Bibliographic Details
Main Authors: Abdul Rehman Khalil Shaikh, Ikram Ujjan, Muhammad Irfan, Arshi Naz, Tahir Shamsi, Muhammad Tariq Masood Khan, Muhammad Shakeel
Format: Article
Language:English
Published: PeerJ Inc. 2021-02-01
Series:PeerJ
Subjects:
AML
TET2
PCR
DNA methylation
Cancer genetics
Coding exons
Online Access:https://peerj.com/articles/10678.pdf

Internet

https://peerj.com/articles/10678.pdf

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