Identification of novel proteins for lacunar stroke by integrating genome-wide association data and human brain proteomes
Abstract Background Previous genome-wide association studies (GWAS) have identified numerous risk genes for lacunar stroke, but it is challenging to decipher how they confer risk for the disease. We employed an integrative analytical pipeline to efficiently transform genetic associations to identify...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2022-06-01
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Series: | BMC Medicine |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12916-022-02408-y |