Molecular Profiling of 22 Primary Atypical Meningiomas Shows the Prognostic Significance of 18q Heterozygous Loss and <em>CDKN2A/B</em> Homozygous Deletion on Recurrence-Free Survival

Molecular Profiling of 22 Primary Atypical Meningiomas Shows the Prognostic Significance of 18q Heterozygous Loss and <em>CDKN2A/B</em> Homozygous Deletion on Recurrence-Free Survival

The use of adjuvant therapy is controversial in atypical meningiomas with gross total resection. Predictors of recurrence risk could be useful in selecting patients for additional treatments. The aim of this study was to investigate whether molecular features are associated with recurrence risk of a...

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Bibliographic Details
Main Authors: Valeria Barresi, Michele Simbolo, Adele Fioravanzo, Maria Liliana Piredda, Maria Caffo, Claudio Ghimenton, Giampietro Pinna, Michele Longhi, Antonio Nicolato, Aldo Scarpa
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Cancers
Subjects:
atypical meningioma
tumor mutational burden
recurrence
<i>NF2</i>
<i>CDKN2A</i>/<i>B</i>
<i>AKT1</i>
Online Access:https://www.mdpi.com/2072-6694/13/4/903

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https://www.mdpi.com/2072-6694/13/4/903

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