MED12 exerts an emerging role in actin-mediated cytokinesis via LIMK2/cofilin pathway in NSCLC

MED12 exerts an emerging role in actin-mediated cytokinesis via LIMK2/cofilin pathway in NSCLC

Abstract Background Mediator complex subunit 12 (MED12) is an essential hub for transcriptional regulation, in which mutations and overexpression were reported to be associated with several kinds of malignancies. Nevertheless, the role of MED12 in non-small cell lung cancer (NSCLC) remains to be elu...

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Bibliographic Details
Main Authors: Meng Xu, Fang Wang, Guibo Li, Xiaokun Wang, Xiaona Fang, Haoxuan Jin, Zhen Chen, Jianye Zhang, Liwu Fu
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Molecular Cancer
Subjects:
MED12
Cytokinesis
Actin
LIMK2
NSCLC
Online Access:http://link.springer.com/article/10.1186/s12943-019-1020-4

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http://link.springer.com/article/10.1186/s12943-019-1020-4

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