An innovative lab-scale production for a novel therapeutic DNA vaccine candidate against rheumatoid arthritis

Abstract Background Recent therapeutic-plasmid DNA vaccine strategies for rheumatoid arthritis (RA) have significantly improved. Our pcDNA-CCOL2A1 vaccine is the most prominent and the first antigen-specific tolerising DNA vaccine with potent therapeutic and prophylactic effects compared with methot...

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Bibliographic Details
Main Authors: Juan Long, Xiao Zhao, Fei Liang, Yang Zeng, Nan Liu, Yuying Sun, Yongzhi Xi
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Journal of Biological Engineering
Subjects:
Online Access:https://doi.org/10.1186/s13036-024-00411-w