Aberrant metabolite trafficking and fuel sensitivity in human pluripotent stem cell-derived islets

Aberrant metabolite trafficking and fuel sensitivity in human pluripotent stem cell-derived islets

Summary: Pancreatic islets regulate blood glucose homeostasis through the controlled release of insulin; however, current metabolic models of glucose-sensitive insulin secretion are incomplete. A comprehensive understanding of islet metabolism is integral to studies of endocrine cell development as...

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Bibliographic Details
Main Authors: Tom Barsby, Eliisa Vähäkangas, Jarkko Ustinov, Hossam Montaser, Hazem Ibrahim, Väinö Lithovius, Emilia Kuuluvainen, Vikash Chandra, Jonna Saarimäki-Vire, Pekka Katajisto, Ville Hietakangas, Timo Otonkoski
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:Cell Reports
Subjects:
CP: Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723009816

Internet

http://www.sciencedirect.com/science/article/pii/S2211124723009816

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