NMR relaxation and diffusion studies to probe the motional dynamics of risperidone within PLGA microsphere

NMR relaxation and diffusion studies to probe the motional dynamics of risperidone within PLGA microsphere

The present study aims to investigate the motional dynamics of risperidone within polylactic co-glycolic acid (PLGA) microsphere by employing solution state 1H and 19F nuclear magnetic resonance (NMR) measurements. Risperidone, a second-generation fluorinated antipsychotic drug used for the treatmen...

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Bibliographic Details
Main Authors: Deepak Kumar, Samanwita Pal
Format: Article
Language:English
Published: KeAi Communications Co. Ltd. 2023-05-01
Series:Magnetic Resonance Letters
Subjects:
Polylactic co-glycolic acid (PLGA) microsphere
Motional dynamics
1H and 19F NMR
Diffusion
Hydrodynamic radius
Cross-correlated relaxation
Online Access:http://www.sciencedirect.com/science/article/pii/S2772516223000177

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http://www.sciencedirect.com/science/article/pii/S2772516223000177

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