Predictive models for mutations in mismatch repair genes: implication for genetic counseling in developing countries

Predictive models for mutations in mismatch repair genes: implication for genetic counseling in developing countries

<p>Abstract</p> <p>Background</p> <p>Lynch syndrome (LS) is the most common form of inherited predisposition to colorectal cancer (CRC), accounting for 2-5% of all CRC. LS is an autosomal dominant disease characterized by mutations in the mismatch repair genes mutL homo...

Full description

Bibliographic Details
Main Authors: Monteiro Santos Erika, Valentin Mev, Carneiro Felipe, de Oliveira Ligia, de Oliveira Ferreira Fabio, Junior Samuel, Nakagawa Wilson, Gomy Israel, de Faria Ferraz Victor, da Silva Junior Wilson, Carraro Dirce, Rossi Benedito
Format: Article
Language:English
Published: BMC 2012-02-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/12/64

Internet

http://www.biomedcentral.com/1471-2407/12/64

Similar Items