Enhanced potency of aggregation inhibitors mediated by liquid condensates

Liquid condensates are membraneless organelles that form via phase separation in living cells. These condensates provide unique heterogeneous environments that have much potential in regulating a range of biochemical processes from gene expression to filamentous protein aggregation—a process linked...

Full description

Bibliographic Details
Main Authors: Thomas C. T. Michaels, L. Mahadevan, Christoph A. Weber
Format: Article
Language:English
Published: American Physical Society 2022-12-01
Series:Physical Review Research
Online Access:http://doi.org/10.1103/PhysRevResearch.4.043173