Nuclear SUN1 stabilizes endothelial cell junctions via microtubules to regulate blood vessel formation

Nuclear SUN1 stabilizes endothelial cell junctions via microtubules to regulate blood vessel formation

Endothelial cells line all blood vessels, where they coordinate blood vessel formation and the blood-tissue barrier via regulation of cell-cell junctions. The nucleus also regulates endothelial cell behaviors, but it is unclear how the nucleus contributes to endothelial cell activities at the cell p...

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Bibliographic Details
Main Authors: Danielle B Buglak, Pauline Bougaran, Molly R Kulikauskas, Ziqing Liu, Elizabeth Monaghan-Benson, Ariel L Gold, Allison P Marvin, Andrew Burciu, Natalie T Tanke, Morgan Oatley, Shea N Ricketts, Karina Kinghorn, Bryan N Johnson, Celia E Shiau, Stephen Rogers, Christophe Guilluy, Victoria L Bautch
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-03-01
Series:eLife
Subjects:
endothelial cells
nuclear LINC complex
SUN1
microtubules
adherens junctions
blood vessels
Online Access:https://elifesciences.org/articles/83652

Internet

https://elifesciences.org/articles/83652

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