The pathogenesis of influenza in intact alveoli: virion endocytosis and its effects on the lung’s air-blood barrier

Lung infection by influenza A virus (IAV) is a major cause of global mortality from lung injury, a disease defined by widespread dysfunction of the lung’s air-blood barrier. Endocytosis of IAV virions by the alveolar epithelium – the cells that determine barrier function – is central to barrier loss...

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Bibliographic Details
Main Authors: Jaime L. Hook, Jahar Bhattacharya
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1328453/full