Regulation Mechanisms of Meiotic Recombination Revealed from the Analysis of a Fission Yeast Recombination Hotspot <i>ade6-M26</i>

Regulation Mechanisms of Meiotic Recombination Revealed from the Analysis of a Fission Yeast Recombination Hotspot <i>ade6-M26</i>

Meiotic recombination is a pivotal event that ensures faithful chromosome segregation and creates genetic diversity in gametes. Meiotic recombination is initiated by programmed double-strand breaks (DSBs), which are catalyzed by the conserved Spo11 protein. Spo11 is an enzyme with structural similar...

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Bibliographic Details
Main Author: Kouji Hirota
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Biomolecules
Subjects:
meiotic recombination
double strand break (DSB)
Rec12 (fission yeast Spo11 homolog)
chromatin
transcription factor
<i>S. pombe</i>
Online Access:https://www.mdpi.com/2218-273X/12/12/1761

Internet

https://www.mdpi.com/2218-273X/12/12/1761

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