Pro-efferocytosis biomimetic nanocomplexes for targeted atherosclerosis therapy through promoting macrophage re-polarization and inhibiting senescence

Pro-efferocytosis biomimetic nanocomplexes for targeted atherosclerosis therapy through promoting macrophage re-polarization and inhibiting senescence

Atherosclerosis is chronic inflammatory disease tightly related with defective efferocytosis of apoptotic cells (ACs) in the plaques. The strategy of efferocytosis reactivation using Atorvastatin (AT) and Metformin (Met) has attracted increasing attention for atherosclerosis treatment. Although thes...

Full description

Bibliographic Details
Main Authors: Peidong You, Anning Yang, Yue Sun, Hongwen Zhang, Yaling Zeng, Yinju Hao, Jiantuan Xiong, Shengchao Ma, Huiping Zhang, Bin Liu, Yideng Jiang
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Materials & Design
Subjects:
Atherosclerosis
Efferocytosis
Macrophage polarization
Senescence
Atorvastatin
Metformin
Online Access:http://www.sciencedirect.com/science/article/pii/S0264127523007311

Internet

http://www.sciencedirect.com/science/article/pii/S0264127523007311

Similar Items