Novel Targeted Therapies for Rheumatoid Arthritis Based on Intracellular Signalling and Immunometabolic Changes: A Narrative Review

Novel Targeted Therapies for Rheumatoid Arthritis Based on Intracellular Signalling and Immunometabolic Changes: A Narrative Review

Rheumatoid arthritis (RA) is a relatively common systemic autoimmune disease with an estimated prevalence of approximately 1% worldwide. Patients present predominantly with symmetrical small joint inflammatory arthritis, which involves dysregulated immune responses, leading to bone and cartilage def...

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Bibliographic Details
Main Authors: Marveh Rahmati, Maria Paula Kwesiga, Jiachen Lou, Ai Lyn Tan, Michael F McDermott
Format: Article
Language:English
Published: IMR Press 2024-01-01
Series:Frontiers in Bioscience-Landmark
Subjects:
rheumatoid arthritis
intracellular signalling pathways
er stress
treatment response
multidrug resistance
autoimmune/autoimmunity
inflammation
refractory ra
metabolic reprogramming/metabolites
Online Access:https://www.imrpress.com/journal/FBL/29/1/10.31083/j.fbl2901042

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https://www.imrpress.com/journal/FBL/29/1/10.31083/j.fbl2901042

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