CF Patients’ Airway Epithelium and Sex Contribute to Biosynthesis Defects of Pro-Resolving Lipids

CF Patients’ Airway Epithelium and Sex Contribute to Biosynthesis Defects of Pro-Resolving Lipids

Specialized pro-resolving lipid mediators (SPMs) as lipoxins (LX), resolvins (Rv), protectins (PD) and maresins (MaR) promote the resolution of inflammation. We and others previously reported reduced levels of LXA4 in bronchoalveolar lavages from cystic fibrosis (CF) patients. Here, we investigated...

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Bibliographic Details
Main Authors: Mickael Shum, Charlie M. London, Maelle Briottet, Khadeeja Adam Sy, Vincent Baillif, Reginald Philippe, Abdolhossein Zare, Sadegh Ghorbani-Dalini, Natacha Remus, Agathe Tarze, Virginie Escabasse, Ralph Epaud, Marc Dubourdeau, Valerie Urbach
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Immunology
Subjects:
specialized pro-resolving mediators
cystic fibrosis
gender specificity
lipidomics
resolution of inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.915261/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.915261/full

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