EIF4A3-mediated biogenesis of circSTX6 promotes bladder cancer metastasis and cisplatin resistance

EIF4A3-mediated biogenesis of circSTX6 promotes bladder cancer metastasis and cisplatin resistance

Abstract Background Cisplatin (CDDP)-based chemotherapy is a standard first-line treatment for metastatic bladder cancer (BCa) patients, and chemoresistance remains a major challenge in clinical practice. Circular RNAs (circRNAs) have emerged as essential regulators in carcinogenesis and cancer prog...

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Bibliographic Details
Main Authors: Wenjie Wei, Kan Liu, Xing Huang, Shuo Tian, Hanfeng Wang, Chi Zhang, Jiali Ye, Yuhao Dong, Ziyan An, Xin Ma, Baojun Wang, Yan Huang, Xu Zhang
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Bladder cancer
circSTX6
miR-515-3p
PABPC1
SUZ12
CDDP
Online Access:https://doi.org/10.1186/s13046-023-02932-6

Internet

https://doi.org/10.1186/s13046-023-02932-6

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