Roles of lysine-specific demethylase 1 (LSD1) in homeostasis and diseases
Abstract Lysine-specific demethylase 1 (LSD1) targets mono- or di-methylated histone H3K4 and H3K9 as well as non-histone substrates and functions in the regulation of gene expression as a transcriptional repressor or activator. This enzyme plays a pivotal role in various physiological processes, in...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-06-01
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Series: | Journal of Biomedical Science |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12929-021-00737-3 |