Roles of lysine-specific demethylase 1 (LSD1) in homeostasis and diseases

Roles of lysine-specific demethylase 1 (LSD1) in homeostasis and diseases

Abstract Lysine-specific demethylase 1 (LSD1) targets mono- or di-methylated histone H3K4 and H3K9 as well as non-histone substrates and functions in the regulation of gene expression as a transcriptional repressor or activator. This enzyme plays a pivotal role in various physiological processes, in...

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Bibliographic Details
Main Authors:	Dongha Kim, Keun Il Kim, Sung Hee Baek
Format:	Article
Language:	English
Published:	BMC 2021-06-01
Series:	Journal of Biomedical Science
Subjects:	Cancer Hypoxia Inflammation Immunity Neurodegenerative diseases
Online Access:	https://doi.org/10.1186/s12929-021-00737-3

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