Persistent T cell unresponsiveness associated with chronic visceral leishmaniasis in HIV-coinfected patients

Persistent T cell unresponsiveness associated with chronic visceral leishmaniasis in HIV-coinfected patients

Abstract A large proportion of HIV-coinfected visceral leishmaniasis (VL-HIV) patients exhibit chronic disease with frequent VL recurrence. However, knowledge on immunological determinants underlying the disease course is scarce. We longitudinally profiled the circulatory cellular immunity of an Eth...

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Bibliographic Details
Main Authors: Nicky de Vrij, Julia Pollmann, Antonio M. Rezende, Ana V. Ibarra-Meneses, Thao-Thy Pham, Wasihun Hailemichael, Mekibib Kassa, Tadfe Bogale, Roma Melkamu, Arega Yeshanew, Rezika Mohammed, Ermias Diro, Ilse Maes, Malgorzata A. Domagalska, Hanne Landuyt, Florian Vogt, Saskia van Henten, Kris Laukens, Bart Cuypers, Pieter Meysman, Hailemariam Beyene, Kasaye Sisay, Aderajew Kibret, Dagnew Mersha, Koert Ritmeijer, Johan van Griensven, Wim Adriaensen
Format: Article
Language:English
Published: Nature Portfolio 2024-05-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-024-06225-2

Internet

https://doi.org/10.1038/s42003-024-06225-2

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