Augmented Antitumor Effect of Unripe <i>Rubus coreanus</i> Miquel Combined with Oxaliplatin in a Humanized PD-1/PD-L1 Knock-In Colorectal Cancer Mouse Model

Immune checkpoint inhibitors (ICIs) have been shown to be extraordinarily effective in patients with colorectal cancer (CRC). However, the current ICIs still have adverse effects and limited efficacy of ICI monotherapy. We used a natural product to overcome the vulnerability of ICIs and tried a comb...

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Bibliographic Details
Main Authors: Eun-Ji Lee, Ju-Hye Yang, Jang-Gi Choi, Hwan-Suck Chung
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/11/18/2876