Inherent mitochondrial activity influences specification of the germ line in pluripotent stem cells
Herein we investigated whether inherent differences in mitochondrial activity in mouse pluripotent cells could be used to identify populations with an intrinsic ability to differentiate into primordial germ cells (PGCs). Notably, we determined that stem cells sorted based on differences in mitochond...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-04-01
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Series: | Heliyon |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844020304965 |