Evaluation of dithiothreitol-oxidizing capacity (DOC) as a serum biomarker for chronic hepatitis B in patients exhibiting normal alanine aminotransferase levels: a pilot study towards better monitoring of disease

Evaluation of dithiothreitol-oxidizing capacity (DOC) as a serum biomarker for chronic hepatitis B in patients exhibiting normal alanine aminotransferase levels: a pilot study towards better monitoring of disease

Background: Alanine aminotransferase (ALT) is the most commonly used serum biomarker for chronic liver diseases (CLDs) but may not accurately reflect hepatic disorders and easily underestimates hepatic fibrosis. The previously revised upper limit of normal (ULN) of ALT (19 U/L for women and 30 U/L f...

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Bibliographic Details
Main Authors: Lumin Yang, Yafei Zhang, Ke Zhang, Zhongping Liu, Tengfei He, Xiaowei Zheng, Lei Li, Elias S J Arnér, Zhenhua Zhang, Jinsong Zhang
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:EClinicalMedicine
Subjects:
dithiothreitol-oxidizing capacity
alanine aminotransferase
sulfhydryl oxidase
chronic liver diseases
complementary biomarker
Online Access:http://www.sciencedirect.com/science/article/pii/S2589537021004600

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http://www.sciencedirect.com/science/article/pii/S2589537021004600

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