Metabolic <i>N</i>-Dealkylation and <i>N</i>-Oxidation as Elucidators of the Role of Alkylamino Moieties in Drugs Acting at Various Receptors

Metabolic <i>N</i>-Dealkylation and <i>N</i>-Oxidation as Elucidators of the Role of Alkylamino Moieties in Drugs Acting at Various Receptors

Metabolic reactions that occur at alkylamino moieties may provide insight into the roles of these moieties when they are parts of drug molecules that act at different receptors. <i>N</i>-dealkylation of <i>N</i>,<i>N</i>-dialkylamino moieties has been associated w...

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Bibliographic Details
Main Author: Babiker M. EH-Haj
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Molecules
Subjects:
<i>N</i>-alkylamino moieties
metabolic <i>N</i>-dealkylation
metabolic <i>N</i>-oxidation
pharmacologic activity
physicochemical properties
<i>N</i>-desalkylamino metabolite drugs
Online Access:https://www.mdpi.com/1420-3049/26/7/1917

Internet

https://www.mdpi.com/1420-3049/26/7/1917

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