Adjunctive simvastatin for treatment-resistant depression: study protocol of a 12-week randomised controlled trial

Adjunctive simvastatin for treatment-resistant depression: study protocol of a 12-week randomised controlled trial

BackgroundA third of patients diagnosed with major depressive disorder (MDD) experience treatment-resistant depression (TRD). Relatively few pharmacological agents have established efficacy for TRD. Therefore, the evaluation of novel treatments for TRD is a pressing priority. Statins are pleiotropic...

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Bibliographic Details
Main Authors: Muhammad I. Husain, Imran B. Chaudhry, Ameer B. Khoso, Mohammad Omair Husain, Raza R. Rahman, Munir M. Hamirani, John Hodsoll, Andre F. Carvalho, Nusrat Husain, Allan H. Young
Format: Article
Language:English
Published: Cambridge University Press 2019-01-01
Series:BJPsych Open
Subjects:
Depressive disorders
low and middle income countries
novel CNS drugs
randomized controlled trial
neuroimmunology
Online Access:https://www.cambridge.org/core/product/identifier/S2056472418000844/type/journal_article

Internet

https://www.cambridge.org/core/product/identifier/S2056472418000844/type/journal_article

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